Class : cestoda- Tapeworms Class: Trematoda-Flukes
TrematodesIntestinal flukes— Heterophyes heterophyes Liver flukes— Fasciola hepaticaPulmonary flukes— Paragonimus westermani Blood flukes -- Schistosoma
Blood flukes
Schistosoma haematobium –Vesical veinsSchistosoma mansoni ----Intestinal veinsSchistosoma japonicum---Intestinal veinsSchistosoma haematobium
Schistosoma haematobiumLife cycle: Definitive host: man Intermediate host: Fresh water snails: (Bulinus ,Physopsis &Biomphalaria)
Epidemiology
PathologyMacroscopic Microscopic
Symptoms
Irritative dermatitis Cough &hemoptysis Febrile reaction Eosinophilia Terminal hematurea Dysurea& frequency of micturition Suprapubic pain pyureaDiagnosis
Urine examination: General Schistosoma eggs Hatching test Radiology Ultra-sound Blood exam & serology Intradermal skin testTreatment
Schistosoma mansoniDistribution Hosts Habitat
Pathology & symptoms
Skin penetration :Immature warms in the lungs Adult warm in the mesenteric veinsEggs in the intestine , liver, lungs….Diagnosis
Stool examination Sigmoidoscopy & intestinal biopsy Serology , skin test, liver biopsyTreatment
Oxamniquine orally : 15 mg \kg 2—4 doses Niridazole Praziquantil
Prevention of schistosomiasis
Reduction of sources of infection Prevent water contamination Snail control Avoid infested water people educationSchistosoma dermatitis
Swimmers itchLiver flukes
Fasciola hepatica Inhabits (sheep,goats & catle) liver & biliary systemLife cycle
Adults in the biliary passages Immature eggs are evacuated with feaces Meracidium invades snails (lymnea spieces) leading (sporocyst, 1st & 2nd generation radia then cercaria) Cercaria encyst as meta cercaria on (aquatic plants & vegitations) ingested by mammalsPathology & symptoms
Diagnosis
Eggs in the stool& deudenal aspirate Skin test Serology
Treatment
Bithionol 30-50 mg\kg on alternate days for 5-15 dosesHalzoun
Intestinal flukesHeterophyes heterophyes Egypt & far east In small intestine of man & fish eating mammals 1st intermediate host: snail ( pirenella spieces) 2nd intermediate host: Fish.
Life cycle
Embryonated eggs in stool Ingested by snail(Sporocyst-radia-cercaria) Cercaria leave the snail encyst as matacercaria on scale fins & gills tail of fish. man infection by eating raw or imperfectly cooked fishDiagnosis: eggs in stool Treatment :Praziquantel
Pulmonary flukesParogonimus westermani: Far east Inhabits : Lungs, pluera & bronchi Definitive host: Human ,domesticated &wild animals 1st intermediate host : snail 2nd intermediate host: fresh water crabs &cray fish
Diagnosis : eggs in the sputum or stool Treatment : Bithionol