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Nail Diseases

By

Dr. Salam Altemimi


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Chronic paronychia

Is infection of the nail fold and matrix by 

candida albicans. There is glazed and red 

swelling of the nail fold with loss of the cuticle. 

There is mild to moderate pain. Occasional 

bead of pus comes out from under the nail fold. 

Ridging and furrowing of nail plate may occur 

due to damage of the matrix. Dark brown 

pigmentation of nail plate occurs in direct 

invasion by monilia. The disease is occupational 

of housewives due to wetness, which lead to 

maceration of the cuticle then the entrance of 

the microorganism.


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Differential diagnosis: acute paronychia is 

bacterial infection of the nail fold. There is 

bright red swelling of the nail fold. The 

inflammation is more severe, the condition 

is more painful.


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Acute paronychia


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Treatment of Acute paronychia

Incision to evacuate the pus.

Oral antistaphylococcal antibiotics e.g. 

cephalexin 250 mg four times daily for 7 

days.


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Treatment of chronic paronychia

Maintain dryness.

Topical clotrimazol cream.

Oral choice is fluconazole 150 mg per 

week for 4 weeks.


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Tinea unguium

(onychomycosis)

It is the dermatophyte (ringworm) 

infection of the nails. Commonly caused 

by trichophyton and epidermophyton. The 

affected nail is roughing, opaque and 

friable. It has an accumulation of 

keratinous debris under it. The diagnosis 

can be confirmed by shaving of the nails 

to find fungus on 20% KOH microscopic 

exam. Also culture on Sabouraud medium 

can be performed.


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Tinea unguium


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Treatment of tinea unguium

The treatment of choice is oral 

terbinafine 250mg daily for 6 weeks in 

fingernail infections and for 12 weeks in 

toenail infections.

Fluconazole 150 mg once a week for 9 

months.

Itraconazole (100 mg capsule) given in 

pulse therapy. The pulse consists of 2 

capsules twice daily for 1 week followed 

by 3 weeks of drug free interval. Two to 3 

pulses is given for fingernail infections 

and 3-4 pulses for toenail infections.


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Dermatosis associated with 

nail involvement

1.

Psoriasis

Pitting

Onycholysis

Discoloration

Subungual thickening

Malformed nails

Splinter hemorrhages


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Psoriasis of the nails


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Dermatosis associated with 

nail involvement

2.

Lichen planus

Longitudinal grooving and ridging

Pterygium


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Lichen planus of the nails


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Lichen planus of the nail


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Alopecia areata-nails


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3.

Alopecia areata

Pitting

4.

Norwegian scabies

Nail plate dystrophy

5.

Eczema and dermatitis

Ridging, thickening and discoloration

6.

Paronychia

Ridging, thickening and discoloration

Dermatosis associated with 

nail involvement


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Onycholysis

It is the separation of the nail plate from 

the nail bed at distal and lateral margins. 


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Onycholysis (from psoriasis)


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Etiology of onycholysis

Idiopathic

Secondary

1.

Dermatosis: psoriasis, fungal infections.

2.

General medical conditions: like 

hyperthyroidism, Raynaud’s phenomenon.

3.

Trauma: like typing, long nails.

4.

Drugs: photo-onycholysis occurs with 

tetracycline or psoralin.


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Nail pitting

It is a tiny, punched out or ices pick 

depressions of the nail plate. Common 

causes are psoriasis, alopecia areata, and 

sometimes a normal variant.


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Koilonychia

The nail is flat or concave has spoon-

shape. It is often thin and brittle. The 

condition associated with hypochromic 

iron deficiency anemia.


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Koilonychia


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Finger clubbing

It is increase in the size and curvature of 

nail plate with loss of the angle between the 

nail plate and the posterior nail fold. It is 

associated with many diseases e.g. 

carcinoma of the bronchus, heart diseases.


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Finger clubbing


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Ingrown toenail

It is the soft tissue of the side of the nail 

(lateral nail fold) is penetrated by the 

edge of the nail plate, resulting in pain, 

sepsis and later the formation of the 

granulation tissue. The great toe is often 

affected. The cause is compression of the 

toe by ill-fitting footwear and cutting of 

the toenail in a half-circle instead of 

straight across.


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Ingrowing toenail


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Treatment of ingrown toenail

Wearing wide and pliable shoes.

Antibiotics.

Cauterization of granulation tissues by 

silver nitrate sticks.

If yet no benefit, avulsion of nail plate or 

removal part of it in continuing cellulitis. 


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Good luck




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