مواضيع المحاضرة: Lymphatic Tissue and the Immune System
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Histology LAB. 3

Lymphatic Tissue and the Immune System
Contains of this LAB.
Lymph node (MH 076 )
Tonsil of Human (MH S276 )
Spleen of human (MHS212 )
Thymus gland (MH 079 )

Edited by F ahad A.

Mosul Medical College 2018 -2019 2th stage

Get it from

www.muhadharaty.com

This copy is used to study tissue s with Histology Guide website

to get a better result and a deeper understanding .
Do not hesitate to ask the doctors of the histology branch .

Histology

1

1 - Lymph node

Capsule
enclosing the node
Cortex
Medulla
It's the inner region of the node
Cortical nodules
All the spherical clusters
Remember lighter center of
nodule s called germinal center

1
3
2
5 Trabeculae
It's connective tissue
that extends inward from
the capsule.
7 Lymphatics at hilus
8

Medullary Sinuses

Intervening spaces in which
lymph flows
4
Paracotical zone
6
صورة مكبرة

2

Notes Structure

Dense connective tissue enclosing the node.
- contains of :-
1- Subcapsular Sinus - space underneath the capsule that receives
lymph from afferent lymphatic vessels .
2- Trabeculae - connective tissue that extends inward from the
capsule .
3- Trabecular Sinuses - spaces alongside trabeculae in which lymph
flows from the subcapsular sinus into the cortex .
Capsule
Outer region of the node .
- contains of :-
with lighter Nodules have ( region adjacent to the capsule - Outer Cortex -1
) germinal center called center
2- Inner Cortex - (paracotex ) region between the outer cortex and the medulla
that is free of nodules.
Cortex
Most inner part of the node .
contains of :- -
1- Medullary Cords
2- Medullary Sinuses - intervening spaces in which lymph flows
Medulla

MH 076 VS Code – .com guide istology H

Lymph Node

ال تقسيم odulesN

1- Primary nodules هي nodules التي تحتوي germinal center
2- Secondary nodules هي nodules التي ال تحتوي germinal center
3- white pulp ال هي nodules التي تحتوي على Central arteries و germinal center
وتوجد في spleen
Remember lighter center of nodule s called germinal center

3

2 - Tonsil

Epithelial lining
TYPE: s tratified Squamous
Non -Keratinized Epithelium
Crypts
Nodules
Spherical clusters الحظ
Germinal center
It's lighter center of nodules الحظ
صورة مكبرة
Lymphocytes
It's Granules dispersed "lymph cell "الحظ

4

Notes Structure

Type of it Stratified Squamous Non -Keratinized Epithelium - covers
the numerous nodules that compromise the tonsil .
Epithelial lining
Infoldings of the epithelium into the underlying connective tissue. Crypts
spherical aggregations of lymphocytes ( have germinal centers ) Lymph Nodules
pass through the epithelium in areas of inflammation . Lymphocytes

Tonsil on Histologyguide.com

76 2 S MH VS Code – Histologyguide.com

5

3 – Spleen

Capsule
Enclosing the organ
Trabeculae
Connective tissue that extends inward Blood vessels

Central arteries

Regular circle in nodule
Splenic sinusoids
Lymphocytes
It's Granules dispersed "lymph cell " الحظ
Red pulp
White pulp
Red pulp االساليد ارضية هي و
Splen ic nodules

6

Notes Structure

Dense connective tissue enclosing the organ . Capsule
connective tissue that extends inward from the Trabeculae
Composed of lymphatic tissue.
It appears basophilic due to the large number of nuclei
White Pulp
Clusters of B lymphocytes located on central arterioles.
They usually contain a germinal center of activated B lymphocytes
Splenic Nodules
branches of trabecular arteries . Central Arterioles
Filters and degrades red blood cells (RBCs).
It appears eosinophilic due to the large number of RBCs
Red Pulp
vascular spaces Splenic Sinusoids

Spleen on Histologyguide.com

212 S MH VS Code – Histologyguide.com

7

4 - Thymus (for adult)

Hassel's Corpuscle
Thymic lobule
Cortex
Medulla
"nd & 2 st It have nodule "1

Lymphocytes

Trabeculae
"septae"
Small nuclei of condensed chromatin.
حواجز
تقسم النسيج لفصوص
Adipose tissue

صورة توضيحية

8

4- Thymus (Neonatal)

Hassel's Corpuscle
Thymic lobule
Cortex
Medulla

Trabeculae

"septae"

Lymphocytes

Small nuclei of condensed chromatin.

9

Notes Structure

thin connective tissue surrounding the thymus that extends inward
as trabeculae to form incomplete lobules.
Capsule
Adult = nner, lighter region of large lymphocytes. Cortex
Neonatal = outer darker, region of small lymphocytes.

It have -

1- T-Lymphocytes
2- Epithelial Reticular Cells
inner, lighter region of larger lymphocytes.
Have " Hassel's Corpuscle "

Hassel's Corpuscle = closely packed, concentrically arranged

epithelial reticular cells.
Medulla

Thymus on Histologyguide.com

079 MH VS Code – Histologyguide.com

11

Questions //

Question : Where else do you find tonsils in the oral cavity?
1 – Palatine tonsils
2 – Pharyngeal tonsils
3 – Lingual tonsil
-------------------------------------------------------------------------
Question : What is the function of tonsils?
They are the immune system's first line of defense against ingested or inhaled foreign
pathogens .
Play role in immunity of the body because they contain B&T - lymphocytes thus they are
important especially in children .
-------------------------------------------------------------------------
Discuss the effects of removing the tonsils .
(A very common procedure not so long ago!)

Question : What is happening to the thymus gland with increasing age?

Is it still functional in the adult?

11

Task : List the major immune cells and their functions


رفعت المحاضرة من قبل: Fahad Ahmed
المشاهدات: لقد قام 5 أعضاء و 23 زائراً بقراءة هذه المحاضرة






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