Tumor Matrix
Osteoblastic
Fluffy, cotton-like or cloud-like densities
Osteosarcoma
Cartilaginous
Comma-shaped, punctate, annular,
popcorn-like
Enchondroma, chondrosarcoma,
chondromyxoid fibroma
Osteoblastic
Cartilaginous
Tumor matrix
Osteosarcoma
Osteoblastic
Cartilaginous
Tumor matrix
Chondrosarcoma
Primary malignant tumors
osteosarcoma
giant cell tumor
chondrosarcoma
primary lympoma
of bone
fibrosarcoma
malignant fibrous
histiocytoma
Ewing sarcoma
Radiological feature of Primary
malignant tumors
poorly defined margin
soft tissue mass
wide zone of transition
irregular margin
the lesion destroy
cortex of bone
Bone destruction
periosteal reaction
Benign tumor
Aneurysmal bone cyst
Brown tumor
osteoma
Enchondroma
simple bone cyst
eosinophilia granuloma
Fibrous dysplasia
•
osteoid ostemoa
Radiological feature of Benign
tumor
Well defined edge
regular margin
expansile
thin cortex
no soft tissue mass
pathological fracture
Little or no periosteal reaction
Benign vs. Malignant
In the Transverse Plane
Central
Enchondroma
Eccentric
GCT, osteosarcoma, chondromyxoid fibroma
Cortical
Non-ossifying fibroma, osteoid osteoma
Parosteal
Parosteal osteosarcoma, osteochondroma
In the Longitudinal Plane
Epiphyseal
GCT, chondroblastoma
Metaphyseal
Osteomyelitis, osteo- and
chondrosarcoma
Diaphyseal
Round cell lesions, ABC, enchondroma
Multiple Myeloma
Expansile lesions
Multiple myeloma
Mets
Aneurysmal bone
cyst
Fibrous dysplasia
Brown tumor
Enchondroma
Lymphoma
•
Renal Cell Carcinoma
Expansile lesions
Multiple myeloma
Mets
Aneurysmal bone cyst
Fibrous dysplasia
Brown tumor
Enchondroma
Lymphoma
•
Aneurysmal Bone Cyst
Expansile lesions
Multiple myeloma
Mets
Aneurysmal bone
cyst
Fibrous dysplasia
Brown tumor
Enchondroma
Lymphoma
•
Fibrous Dysplasia
Expansile lesions
Multiple myeloma
Mets
Aneurysmal bone
cyst
Fibrous dysplasia
Brown tumor
Enchondroma
Lymphoma
•
Brown Tumor
Expansile lesions
Multiple myeloma
Mets
Aneurysmal bone
cyst
Fibrous dysplasia
Brown tumor
Enchondroma
Lymphoma
•
Enchondroma
Expansile lesions
Multiple myeloma
Mets
Aneurysmal bone
cyst
Fibrous dysplasia
Brown tumor
Enchondroma
Lymphoma
•
Lymphoma
Expansile lesions
Multiple myeloma
Mets
Aneurysmal bone
cyst
Fibrous dysplasia
Brown tumor
Enchondroma
Lymphoma
•
Tumor Types
Characteristic Locations
Simple bone cyst
Proximal humerus
Chondroblastoma
Epiphyses
Giant Cell tumor
Epiphyses
Simple bone cyst
Proximal humerus
Chondroblastoma
Epiphyses
Giant Cell tumor
Epiphyses
Characteristic locations
Chondroblastoma
Simple bone cyst
Proximal humerus
Chondroblastoma
Epiphyses
Giant Cell tumor
Epiphyses
Characteristic locations
Giant Cell Tumor
Simple bone cyst
Proximal humerus
Chondroblastoma
Epiphyses
Giant Cell tumor
Epiphyses
Characteristic locations
Eosinophilic
granuloma
Neuroblastom
a
Leukemia
Lytic Lesions in Children
Eosinophilic granuloma
Leukemia
Eosinophilic
granuloma
Neuroblastoma
Leukemia
Lytic Lesions in Children
Sclerotic Cortical Lesions
Healing Stress
Fracture
Osteoid Osteoma
Brodie’s abscess
Patterns of Destruction
Geographic
Moth-eaten
Permeative
Less malignant
More malignant
Geographic Bone Destruction
Destructive lesion with sharply
defined border
Implies a less-aggressive, more slow-
growing, benign process
Narrow transition zone
Non-ossifying fibroma
Geographic
Moth-eaten
Permeative
Patterns of Bone Destruction
Geographic Lesions
Examples
Non-ossifying fibroma
Chondromyxoid fibroma
Eosinophilic granuloma
Leukemia
Patterns of Bone Destruction
Geographic
Moth-eaten
Permeative
