Blood Physiology Lec. 1
Dr. Basim A. Al-Ka’abi
MBChB (Medicine)
MSc, PhD (Medical Physiology)
The blood:
• Definition
• Contents and their proportions
• Total blood volume
Red blood cells:
• Total number
• Dimensions
• Life span
Red blood cells (cont’d):
• Red cell membrane permeability
• Major function
• Carbonic anhydrase
Red blood cells (cont’d):
• Hematocrit?
White blood cells:
• Definition
• Sites of formation
• Proportion in relation to RBCs
• Subtypes
Neutrophils:
• Type and percentage
• Nucleus and cytoplasmic granules
• Main target microorganism
Neutrophils (cont’d):
• Phagocytosis
• Chemotaxis?
Eosinophils:
• Type and percentage
• Nucleus and cytoplasmic granules
• Main target microorganism
• Role in allergic reactions
Basophils:
• Type and percentage
• Nucleus and cytoplasmic granules
• Similarity to mast cells
Basophils (cont’d):
• IgE-related allergic reaction
• Secretion of heparin, histamine and bradykinin
• Role in reducing inflammation
• Phagocytic?
Lymphocytes:
• Type and percentage
• Nucleus and cytoplasm
• Site of formation
Lymphocytes (cont’d):
• Subtypes
• T-cell, function
• B-cell, function
Monocytes:
• Type and percentage
• Size, nucleus and cytoplasm
• Phagocytosis, macrophages?
Life span of WBCs:
• Granulocytes, infection?
• Monocytes, in circulation and tissues
• Lymphocytes, continual circulation and body’s need
Good Luck