Blood Physiology Lec. 7
Dr. Basim A. Al-Ka’abi
MBChB (Medicine)
MSc, PhD (Medical Physiology)
Hemostasis:
• Meaning
• Main mechanisms
Vascular spasm:
• Benefit
• Cause
Formation of platelet plug:
• Meaning
• Change in platelet characteristics
Blood coagulation:
• Main essential steps
• Meaning of extrinsic and intrinsic pathways
Extrinsic pathway:
• Main steps
• Role of tissue factor and phospholipid
Intrinsic pathway:
• Main steps
• Role of platelet phospholipids
Thrombin formation:
• Conversion of prothrombin to thrombin
Fibrin formation:
• Conversion of fibrinogen to fibrin
Clot retraction:
• Duration
• Fluid expressed
• Role of platelets
Fibrinolysis:
• Definition
• Main enzyme involved
• Benefit
Good Luck