Insulin therapy
Dicovered in 1921
Extracted from pigs and cows
Recently=DNA recombonent technology
THE ONLY DRUG WITH NO MAXIMUM DOSE
It’s the only pure anabolic hormone
types
Soluble
=
clear
=
short acting
=
regular
=
unmodified
Insoluble
=
cloudy
=
intermediate
=
depot
=
modified
Addition of protamine
+
zinc=isophane
or
NPH insulin
Addition of zinc ions
=
lente
Available in
100
units/ml
Roots
=
IV
+
IM
+
SC
+
INHALOR
+
INTRAPERITONEAL
+
CONTINEOUS
oral(?????)
+
S.C INSULIN INFUSION(
SCII
)
WARMING
+
EXCERSICE
+
LOCAL MASSAGE
=
INCREASE ITS
ABSORPTION
ANT ABD. WALL
=
UPPER ARMS
=
OUTER THIGHS
=
BUTTOCKS
SHORT
+
LONG ACTING INJ.
15-30 MIN BEFORE
MEAL
RAPID ACTING INJ.
IMMEDIATELY
REMOVED BY LIVER
+
KID
T ½=10 MIN.
SIDE
EFFECTS
=
HYPOG.+LIPODYSTROPHY
+
WT.GAIN
+
ALLERGY(RARE)+P
ERIPHERAL EDEMA
+
AUTO.AB
INJ. SITES
REGULAR INJ
.
PEN
PUMP
INHALOR
INHALORS
INJ. TECH
LIPODYSTROPHY
LIPODYSTROPHY
THANK YOU