NEUROMUSCULAR
BLOCKERS
DR. HUSSAIN ADDAY ALJABERY
M.B.CH.B . M.SC. FICMS ( RAD. )
PHARMACOLOGY
GANGLION BLOCKING DRUGS
•
Trimethaphan and mecamylamine are competitive blockers of ACh at
nicotinic receptors at both sympathetic and parasympathetic ganglia.
•
Because of lack of selectivity and numerous adverse effects, they are
used rarely in the clinical setting hypertensive emergencies).
