fungal infection

Systemic fungal infection(Mycosis)

Candidiasis
candida albicans infectionImmune compromised Pt.Skin and M.M. candidiasisOphthalmic C.  loss of vision Chronic hepatosplenic C.in leukemiaOsteoarthritis , meningitis , endocarditisTreatment:* Amphotericin B, or Flucanazole,

Aspergillosis

aspergillus fumigatus Mainly respiratory Atopic Asthma Aleveolitis Aspergilloma a fungal ball Invasive pul. Asp.


Investigation: Chest x-ray Sputum ; fungal hyphae Eosinophilia & elevated IgE Treatment: Prednisone +- itraconazole Surgical removal Amphotericin + flucytocin iv in sever cases

Histoplasmosis

Histoplasma Capsulatum Inhalation. C/F : Fever , cough, pleurisy , dyspnea, wt. loss Chest X-ray opacity + lymph node Rx: Amphotericin B +-prednisolone or Itraconazole

Cryptococcosis

Cryptococcus neoformans granulamatous lesion in the lung , bones , brain and meninges CSF shows: Lymphocytosis High CSF pressure, Hyphae of the fungus Rx : amphotericin+ flucytocine