مواضيع المحاضرة: Dense connective tissue
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Contain of the same competent 

found in connective tissues, but 

there are fewer cells and ground 

substance.

Dense connective tissue can be 

classified according to the 

arrangement of fibers into

:


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Irregular connective tissue

In this section the collagen fibers are arrange in 

bundle, and form three dimensional network to 

provide resistance to stress from all directions, it 

can be seen in the dermis of skin.

Regular connective tissue

In this section the collagen fibers are arranges in 

regular bundles, it's resistant to tension from one 

direction, it can be classified according to the 

type of fibers to:


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Irregular dense con. t.


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C .S in Tendon (low magnification)


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White fibrous connective tissue

Tendons are the most common of the white 

fibrous. They have parallel, and closely packed 

bundles of collagens (the primary bundles) 

separated by small amount of ground substance. 

Their fibroblast called tendon cell, contain 

elongated nuclei parallel of fibers.

Tendon is surrounded by a sheath of dense con.t. 

Called epitendineum, while secondary bundles 

covered with peritendineum, and the primary 

bundles covered with endotendineum.


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Elastic connective tissue

Is composing of bundles of thick, and parallel 

elastic fibers. The space between these fibers 

is occupied by thin collagen fibers and 

flattened fibroblast. It's called elastic because 

it's yellow color and great elastic. It's present 

in ligaments of vertebral.


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Skeletal con.t.

Cartilage: - consists of cells called 

chondrocytes and ground substance contain 

chondroitin sulfates.

There are three kinds of cartilage:

Hyaline cartilage

Elastic cartilage

White fibro cartilage 


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Hyaline cartilage:-

It’s present in the cartilage of nose larynx, 

trachea and bronchi also in vertebral ends of rib

Chondrocyte is single or aggregate as groups 

called cell nest, it's surrounded with capsule and 

it's found with lacuna in ground substance.

Ground substance appears as hyaline (glass) and 

contains fewer amounts of white fibers so it is 

called hyaline cartilage.

It's surrounded with perichondrium which consist 

of two layers to protect and repair the cartilage.


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Elastic cartilage:-

It's present in auricle of the ear and Eustachian tube.

It's identical to hyaline cartilage except it contains 

bundles of elastic fiber.

Its surrounded with perichondrium

White cartilage:-

Its found in intervertebral disc

Ground substance contains bundles of white fibers in 

parallel arrangement.

It's never present in alone but associated with hyaline 

cartilage or dense fibrous tissue, because, it lack 

perichondrium


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Fibrocartilage


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Bone: - is a specialized connective tissue 

composed of intercellular calcified material 

(bone matrix) and three types of cells: 

osteocyte, which found in lacunae within the 

matrix; osteoblast, which is multinucleated 

giant cell in the matrix called Howship's 

lacunae.


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Compact bone

Its shown in long bone diaphysis, in this 

section, lamellae is regularly arranged around 

Haversian's canal and determined by blood 

vessels and nerves, this complex system 

called Haversian's system. Haversian's canal 

connects with others by Volkmann's canal, 

and between Haversian system there are 

interstitial lamellae. 


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Spongy bone

It's found in bulbous ends of long bones 

called epiphysis. Bone matrix appears as 

irregular trabeculae spongy, there is cavities 

between these trabeculae contain red bone 

marrow and three kinds of cells: osteocyte, 

osteoblast, and osteoclast.


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Endochondral ossification:

This type of ossification is responsible for formation of short and long bone:-

Reserve zone: compose of hyaline cartilage, its present nearest to the end of bone.

Zone of proliferation: is an active zone showing numerous mitosis, each row 
consist of a numbers of flat cells separated by little matrix.   

Zone of maturation: mitosis no longer, the cells and lacunae enlarge becoming 
cubical in shape.

Zone of calcification: the matrix surrounded the enlarged lacunae and deposition 
of mineral within it.

Zone of retrogression (erosion): the cartilage cells die and undergo dissolution; 
there are thicker plates of matrix between rows of cells.

Zone of ossification: osteoblasts differentiate from mesenchymal cells of the 
marrow tissue.

Zone of resorption: in this zone, the marrow cavity increases in size, owing to 

resorption of bone in the center of diaphysis.


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Reserve zone

Proliferation zone

Maturation zone

Calcification zone

Erosion zone

Ossification zone

Resorption zone


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Reserve 

stage

Proliferation 

stage


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Maturation 

stage

calcification 

stage


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calcification 

stage

erosion 

stage

ossification 

stage


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resorption 

stage




رفعت المحاضرة من قبل: Dr-Ali Al-Omran
المشاهدات: لقد قام 42 عضواً و 918 زائراً بقراءة هذه المحاضرة








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