Invasive mole
Gross appearance of invasive mole. A hemorrhagic mass has permeated half of the thickness of the myometrial wall.Intermediate between the HM and chorioca is the invasive mole. Despite its invasive properties in that it may invades into the myometrium and even through the uterine wall and extension into the vagina, there are still villi and thus the mole is not malignant. It may also embolizes to the lungs. Curretement alone may not achieve removal, so chemotherapy may be needed to produce resolution.
Whole-mount view of invasive mole. Abnormal villi are seen permeating the thickened myometrium (arrows).
Hydropic villi covered by proliferating trophoblast are seen permeating the myometrium in this invasive mole.
Invasive mole