Typical cross-section of yellowish, spherical neoplasm in one pole of the kidney. Note the tumor in the dilated, thrombosed renal vein (arrow).
Renal cell carcinoma
The tumor is arising in the lower pole of the kidney. It is fairly circumscribed. The cut surface demonstrates a variegated appearance with yellowish areas, white areas, brown areas, and hemorrhagic red areas. Though these neoplasms are usually slow-growing, they can often reach a considerable size before detection because there is a lot of room to enlarge in the retroperitoneum and there is another kidney to provide renal function. Thus, presenting symptoms and signs usually include flank pain, mass effect, and hematuria.
Renal cell carcinoma
This renal cell carcinoma is very large, as indicated by the 15 cm ruler. A portion of normal kidney protrudes at the lower center. This patient was a physician himself and just didn't have any early symptoms.
Renal cell carcinoma
Well-defined nests of the tumor cells that appear clear (lipid-laden) with well defined cell membranes. The nuclei are usually small and round
Renal cell carcinoma, clear cell type
The tumor is in the lower pole of the kidney with the characteristic tan to gray color and well-circumscribed margins.
Wilms' tumor
Triphasic histology of Wilms' tumor: the stromal component is composed of spindle-shaped cells in the less cellular area on the left; the immature tubule in the center is an example of the epithelial component, and the tightly packed blue cells the blastemal elements.
Wilms' tumor