Pregnenolone: produced directly from cholesterol, the precusor molecule for all C18, C19 and C21 steroids Progesterone: a progestin, produced directly from pregnenolone and secreted from the corpus luteum, responsible for changes associated with luteral phase of the menstrual cycle, differentiation factor for mammary glands Aldosterone: the principal mineralocorticoid, produced from progesterone in the zona glomerulosa of adrenal cortex, raises blood pressure and fluid volume, increases Na+ uptake.
Aldosterone: the principal mineralocorticoid, produced from progesterone in the zona glomerulosa of adrenal cortex, raises blood pressure and fluid volume, increases Na+ uptake Testosterone: an androgen, male sex hormone synthesized in the testes, responsible for secondary male sex characteristics, produced from progesterone Estradiol: an estrogen, principal female sex hormone, produced in the ovary, responsible for secondary female sex characteristics Cortisol: dominant glucocorticoid in humans, synthesized from progesterone in the zona fasciculata of the adrenal cortex, involved in stress adaptation, elevates blood pressure and Na+ uptake, numerous effects on the immune system
Steroid hrs. Characterized by the presence of double bonds which are referred to by the No. Of the preceding carbon atom that is involved with the label of delta . Note the No. Referred to the initiation or beginning Of the double bond example:
Mean double bond start from C 3 to C4, and so on.
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